Engineer in biology studies

Job Description

Job Description
The “Insulin and glucose signalling, Glucotoxicity” team at the Institut Cochin is recruiting
(in French and English) an experienced, independent and dynamic engineer who wishes to contribute to a

research project aimed at characterizing molecular mediators and cellular targets
insulin in maintaining intestinal barrier function. The project involves
already established collaborations (partners in immunology, microbiology, and gastroenterology
clinic), and the candidate will benefit from a highly diverse local environment as well as
the use of ad hoc technologies. The success of this project is based on raising a few
technical obstacles in connection with the technological platforms of the Cochin Institute.

The team “Insulin and Glucose Signaling, Glucotoxicity” located at Institut Cochin is recruiting
an experienced, independent and dynamic engineer who would like to contribute to a research
project aiming at characterizing the molecular mediators and cellular targets of insulin action
in the maintenance of intestinal barrier function. The project involves established
collaborations (partners in immunology, microbiology, and clinical gastroenterology), and the
candidate will benefit from a highly diversified local environment as well as the use of ad hoc
technologies. The success of this project relies on lifting few technical locks in connection with
the technological platforms of the Cochin Institute.

Activities  Choose, develop and adapt experimental and analytical protocols

Main  Conduct a set of techniques related to the needs of the project
(in French and English)  Molecular biology and biochemistry 

Immunocyto/histochemistry and imaging 

 Flow cytometry

Culture of organoids 

Management of murine lines, genotyping and animal experimentation

Select, develop and adapt experimental and analytical protocols 

Conduct a set of techniques related to the needs of the project 

Molecular biology and biochemistry 

Immunocyto/histochemistry and imaging 

Flow cytometry 

Organoid culture 

Murine line management, genotyping and animal experimentation

Activities  Writing of experimental protocols

Associates  Management and organization of technical means within the framework of the project
(in French and English)  Synthesis of results (image analysis and statistics) and reports

weekly 

In-house training in principles and implementation of experiments 

Scientific and technological watch in the field of activity

Drafting of experimental protocol 

Management and organization of technical means within the framework of the

project

National Institute of Health and Medical Research 

Synthesis of results (image analysis and statistics) and weekly reports 

Internal training in the principles and implementation of experiments 

Scientific and technological watch in the field of activity

Knowledge  Theoretical and practical knowledge in biology (notions in physio-
(in French and in English) intestinal pathology, metabolism or stem cell biology being

appreciable) 

Health and safety regulations 

Legal and ethical framework 

Applied Computing 

Good command of English

Solid theoretical and practical knowledge in biology (notions in intestinal

physiopathology, metabolism or stem cell biology being appreciated) 

Health and safety regulations 

Legal and ethical framework 

Applied computer science 

Proficiency in english

Know-how Coordination of tasks for the realization of experimental approaches of:
(in French and English)  Molecular biology 

Cell culture 

Animal experimentation 

 Flow cytometry

Immunohisto/cytochemistry and imaging

Tasks coordination for the execution of experimental approaches related to: 

Molecular biology 

Cell culture 

Animal experiment 

Flow cytometry 

Immunohisto/cytochemistry and imaging

Abilities  Teamwork, interpersonal skills and sense of mutual aid
(in French and English)  Thematic and technical adaptability 

Organization and scientific rigor 

Curiosity and motivation on various ongoing projects in the laboratory 

Autonomy and ability to solve problems 

Synthesis and communication skills

Teamwork, interpersonal skills and sense of mutual aid 

Good thematic and technical adaptability 

Good organization and scientific rigor skills 

Curiosity and motivation on different projects in progress in the laboratory 

Autonomy and ability to solve problems 

Synthesis and communication skills

Specificities) /
None

Constraint(s)

of the post None
(in French and English)

Experience 1 to 5 years of proven experience in a laboratory